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Contrasted
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Parkinson's disease is an incurable illness of the nervous system involving the neuro-transmitters in the brain
- shaking in body and limbs
- Parkinson's disease seems to concentrate more on physical handicaps
- Alzheimer's disease appears to afflict the mental abilities prior to the motor skills and physical skills deteriorating
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Compared
- afflict around 500,000 individuals annually
- symptoms of Alzheimer's and Parkinson's disease can be very much alike and possibly develop along the same lines
- both diseases progress as the years go by
- both are a neurodegenerative disorder
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Symptoms of Parkinson's
- Rigidity
- anxiety
- stress
- skin problems
- insecurity
- male erectile dysfunction
- slowed, quieter speech, and monotone voice
- urinary frequency/urgency
- increased sweating
- dementia(more in elderly)
- diminished sense of smell
- difficulty swallowing and excessive salivation
- depression
- memory loss(more in elderly)
- constipation
- confusion(more in elderly)
- Postural instability
- Parkinsonian gait
- Bradykinesia
- tremors
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Parkinson's medications
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levodopa (Sinemet)
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side effects
- dizziness upon rising
- confusion
- movement disorders
- nausea
- hallucinations
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Symptoms of Alzheimer’s
- Problems of memory, particularly for recent events (short-term memory)
- Mild personality changes, such as less spontaneity, apathy, and a tendency to withdraw from social interactions
- problems in abstract thinking and in other intellectual functions develop
- disturbances in behavior and appearance for example agitation, irritability, quarrelsomeness, and a diminishing ability to dress appropriately.
- affected individuals may become confused or disoriented about what month or year it is
- unable to describe accurately where they live, or be unable to name a place being visited
- patients may wander, be unable to engage in conversation, erratic in mood, uncooperative, and lose bladder and bowel control
- persons may become totally incapable of caring for themselves
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Alzheimer medications
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medication based
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cholinesterase inhibitors
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block the breakdown of acetylcholine, more acetylcholine is available in the brain
- donepezil hydrochloride (Aricept)
- side effects
- stomach ulcers
- abnormal heart beats
- fainting
- joint pain
- insomnia
- increased frequency of urination
- Seizures
- vomiting
- nausea
- dizziness
- fatigue
- generalized pain
- headache
- muscle cramping
- loss of appetite
- weight loss
- diarrhea
- rivastigmine (Exelon)
- side effects
- weight loss
- fainting
- Seizures
- vomiting
- loss of appetite
- dizziness
- nausea
- low blood pressure
- depression
- galantamine (Razadyne - previously called Reminyl)
- side effects
- fatigue
- headache
- vomiting
- abdominal pain
- depression
- fainting
- diarrhea
- weight loss
- nausea
- tacrine (Cognex)
- side effects
- skin rash
- vomiting
- diarrhea
- abdominal pain
- indigestion
- nausea
- liver damage
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partial glutamate antagonists
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Memantine (Namenda)
- partially decreases the effect of glutamate to activate nerve cells
- most common side effects
- fatigue
- pain
- increases in blood pressure
- dizziness
- headache
- constipation
- vomiting
- back pain
- confusion
- somnolence
- hallucination
- coughing
- difficulty breathing
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non-medication based
- maximizing patients' opportunities for social interaction and participating in activities such as walking, singing, dancing that they can still enjoy.
- cognitive rehabilitation, (whereby a patient practices on a computer program for training memory)
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Patient education
- provide a safe living environment
- additional medical help may be needed as disease progresses
- take any medication as perscribed