1. REPORT
   1. FOREST PLOT
   2. APPRAISE WITH QUOROM STATEMENT
2. PUBLICATION BIAS
   1. FUNNEL PLOT
   2. GALBRIATH PLOT
   3. EGGER TEST
   4. ROSENTHAL'S FAIL-SAFE N
3. METHODS
   1. GRAPHICAL METHODS
      1. FOREST PLOT
      2. GILBRAITH PLOT (RADIAL DIAGRAM)
      3. PLOT OF NORMALIZED Z SCORE
      4. L'ABBE PLOT
   2. COCHRANE'S Q STATISTIC (OR CHI-SQ TEST)
4. Heterogenity
   1. causes
      1. 1. chance 2. Diff outcome measures 3. Diff Rx charac 4. Study design and conduct
   2. dealing with it
      1. Change scale of outcome variable
      2. Meta-regression
      3. Sensitivity analysis
      4. Subgroup analysis
5. The clinical Question
   1. Protocol - clearly defined, explicit
      1. Literature search - with predetermined protocol
         1. Inclusion & Exclusion of studies
            1. Check that with 2-3 diff assessors
            2. Check for HETEROGENEITY
            3. STUDIES ARE HOMOGENOUS
            4. MA WITH FIXED EFFECTS MODEL
            5. MANTEL-HAENSZEL PROCEDURE
            6. PETO METHOD
            7. HETEROGENITY FOUND
            8. MA WITH RANDOM EFFECTS MODEL