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Characteristics
- Genetic Material: Either DNA or RNA
- Can't replicate without a host cell
- Can't divide by binary fission, Mitosis or Meiosis
- Can't make energy (get it from Host cell)
- Can't make their own Protein or Genetic material (steal it from host cell)
- Intracellular Parasites
- Size range from 10-300 nm
- Can infect all Organisms
- Genetic Material surrounded by Capsid or Protein coat (Small protein units called Capsomeres)
- Some have an outer envelope
- May also have tail, sheath and tail fibres
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Classification
- Type of genetic Material
- shape and/or size of Caspid
- Number of Capsomeres
- Presence or absence of an envelope
- Type of hosts it infects
- Type of disease it produces
- Target cell
- Immunologic or antigenic properties
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Host Range
- Is the spectrum of host cells the virus can infect
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Mostly single host range
- Invertebrates
- Vertebrates
- Plants
- Protists
- Bacteria
- Fungi
- Rarely cross the hist range Barrier
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Determined by
- Attachment sites on the host
- Availability in the potential host the factor for viral replication
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Origin
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3 Major theories
- Viruses are remnants of past infections
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Cells came before viruses
- Viruses are degenerate cells or cell fragments
- Viruses represent a separate evolutionary branch
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Attachment sites
- Outer surface of virus interact with specific receptor sites on surface of potential host cell
- Complementary component held together by hydrogen bonds
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Antiviral agents
- Interfere with the Phases of viral multiplication
- May disrupt an enzyme or protein
- May interfere with the synthesis of viral parts like DNA, RNA or Protein synthesis
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Some Viruses
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Retroirus
- Genetic information is single stranded RNA
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Have a special enzyme called Reverse Transcriptase
- Makes DNA from RNA
- Integrate their newly formed double stranded DNA into the host cell
- Many Retroviruses are responsible for junk DNA in our genome
- Plant Virus
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Bacteriophage
- Viruse that infects Bacteria
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Types
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Virulent Bacteriophage
- Causes lytic cycle
- Steps
- Attachment
- Penerration
- Biosynthesis
- Assembly
- Release
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Temperate Bacteriophage
- Do not immedietly begin lytic cycle
- DNA remains embedded in Bacterial cell Chromosome
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Animal Viruses
- Attach to Specific binding sites on cells
- This affects what species and which cell type is infected
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Multiplication of Animal Viruses
- Attachment
- Penetration
- Uncoating
- Biosynthesis
- Assembly
- Release
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Oncogenic Viruses
- Viruses that cause cancer
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Taxonomy
- Based on guideline by ICTV (International Committee on Taxonomy of Viruses)
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Grouping based on
- Nucleic acid type
- Strategy of replication
- Mosphology
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Names
- Older names: end with - ales
- Family Name: end with- Viridae
- Genus Name: End with - Virus
- Species name: Described by common name
- Subspecies name:Designated by number