1. Head/Brain/Neuro
   1. Head
      1. Headache
   2. Brain
      1. Visual damage, Hearing loss
   3. Neurological
      1. "Chemo brain", Cognitive Changes, Peripheral neuropathy, Dizziness, Vertigo, Neurotoxicity, Ataxia, Speech Difficulties
   4. Psychological
      1. Depression, Anxiety, Insomnia, Fear, Distress
2. Cardiovascular, Circulatory, and Immune
   1. Cardiovascular
      1. Cardiotoxicity, Cardiomyopathy, Arrhythmia, Increased Risk of Heart Attack
   2. Circulatory & Immune Systems
      1. Anemia
         1. Bruising, Feeling Cold
      2. Leukopenia
         1. Increased Risk of Infection, Fever
      3. Thrombocytopenia
      4. Neutropenia
      5. Tumor Lysis Syndrome
3. Gastrointestinal
   1. Mouth
      1. Mucosities, Thrush, Metallic Taste
   2. Upper GI
      1. Nausea, Vomiting, Stomach Pain
   3. Lower GI
      1. Constipation, Diarrhea, Bloody Stools
   4. Liver
      1. Hepatotoxicity
4. Urinary
   1. Nephrotoxicity
   2. Edema
      1. Ascites
   3. Bladder Irritation
      1. Cystitis
   4. Electrolyte Fluctuation
      1. Hypercalcemia
5. Sexual and Reproductive
   1. Male
      1. Lower Sperm Count
      2. Temporary or Permanent Infertility
   2. Female
      1. Hot Flashes
      2. Irregular Periods
      3. Sudden Onset Menopause
      4. Temporary or Permanent Infertility
      5. Vaginal Dryness
      6. Risk of Vaginal Infections
6. Musculoskeletal
   1. Weakness
   2. Lethargy
   3. Fatigue
   4. Aching Muscles
   5. Slowed Small Motor Skills
   6. Slowed Reflexes
   7. Bone Loss
      1. Osteoporosis
         1. Risk of Fractures
   8. Loss of Balance
      1. Clumisness
   9. Shaking or Trembling
7. Respiratory
   1. Pulmonary Toxicity
   2. Pneumonitis
   3. Pulmonary Fibrosis
8. Hair, Skin, and Nails
   1. Hair
      1. Alopecia
         1. Eyelashes, Eyebrows, Body Hair, Hair
   2. Skin
      1. Peeling, Dryness, Pruritus, Acne, Rash, Sun sensitivity
   3. Nails
      1. Color changes, Texture changes, Brittleness