- - High renin sec. -> high aldosteron =Secondary hyper-aldosteronism ( MCC renal artery stenosis, juxtaglomerular renin secreting cell tumor)
- normal or low renin & High aldosteron sec. = Primary hyper-aldosteronism ( MCC bilateral idiopathic adrenal hyperplasia, or Conn's Disease(=Adenoma) )
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Hypertension=higher than 140/60, or higher than 130/80 in DM
- 1ry=essensial=MCC
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2ry
-
hypo-k
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Plasma Aldosterone to Renin ratio
- High i.e 30 or more
- Dx. Primary hyperaldosteronism(Conn's or Hyperplasia)
- Dx.Conn's
- Rx. Surgery
- Dx. hyperplasia
- Rx. spironolactone
- low
- Dx. juxtaglomerular tumor
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stenosis of renal artery ->bruit
- renal artery stenosis (=Secondary hyper-aldosteronism )
- young female
- Fibromuscular type
- Rx. Surgery
- old male
- atherosclerotic type
- Hypotension=Shock=lower than 90/60