1. side effects
   1. leukemia
2. gene repair
   1. homologous recombination
   2. single nucleotide mutation
3. hereditary disease
   1. homozygous
   2. heterozygous
4. Main Topic 5
5. vector
   1. retrovirus
   2. adenovirus
   3. AAV (adeno associated virus)
   4. liposome
   5. insertion in the genome
      1. activation of oncogenes
      2. high transcription
6. clinical trial
7. emerging field