1. Hormones
   1. secretion
      1. gland
         1. endocrine
            1. into
            2. blood
            3. affect
            4. cells
            5. ductless
         2. exocrine
            1. into
            2. space
2. Function
   1. maintain
      1. constant
         1. internal
            1. environment
            2. chemically
            3. substance
            4. waste
            5. CO2
            6. Urea
            7. nutrients
            8. glucose
            9. protein
            10. concentration
            11. water
            12. ions
            13. physically
            14. temperature
3. Mechanism
   1. Negative Feedback
      1. Components
         1. sensors
            1. detect
            2. status
            3. changes
            4. from
            5. norm
         2. control center
            1. indicate
            2. norm
            3. when
            4. at
            5. norm
            6. turn off
         3. effectors
            1. activates
            2. retain
   2. Positive Feedback
      1. concept
         1. exaggerate
            1. amplify
            2. already
            3. there
4. Blood sugar level
   1. diabetes
      1. disease
         1. blood
            1. sugar
            2. level
            3. high
      2. Type 1
         1. Juvenile
         2. reason
            1. insulin
            2. lack
            3. genetic
            4. damage
            5. pancreas
      3. Type 2
         1. adult
            1. onset
         2. reason
            1. insulin
            2. resistant
            3. cells
            4. not
            5. responding
            6. muscle
            7. liver
            8. fat
      4. diagnosis
         1. when
            1. fasting
         2. interpret
            1. <100
            2. normal
            3. 100-125
            4. alarming
            5. >125
            6. diabetes
      5. Risk factors
         1. age
            1. <45
         2. obesity
            1. BMI
            2. >25
         3. acvities
            1. exercises
         4. family
            1. history
            2. related
            3. genes
         5. ethnicity
            1. african American
            2. hispanic
            3. Asian American
            4. American Indian
         6. blood
            1. pressure
            2. high
         7. lipid
            1. level
            2. low
            3. HDL
            4. cholesterol
            5. <35
      6. effects
         1. heart
            1. diseases
            2. Ischemic
            3. heart
            4. disease
         2. brain
            1. cerebrovascular
   2. Regulation
      1. low
         1. release
            1. glucagon
            2. transorm
            3. glycogen
            4. to
            5. glucose
            6. alpha cell
            7. pancreas
      2. high
         1. release
            1. insulin
            2. transform
            3. glucose
            4. to
            5. glycogen
            6. store
            7. liver
            8. encourage
            9. cells
            10. take
            11. up
            12. glucose
            13. d
            14. beta cell
            15. Pancreas
5. Thermoregulation in Endotherms (Mammals, Birds)
   1. heat center
      1. brain
         1. hypothalamus
            1. thermoreceptor
            2. skin
            3. dermis
            4. receive
            5. signal
            6. change
            7. temperature
            8. if
            9. too
            10. hot
            11. cold
         2. Effectors reaction
            1. capillary bed
            2. vasodilation
            3. vasocontraction
            4. sweat gland
            5. open
            6. sweat
            7. evaporation
            8. close
            9. hair
            10. relax
            11. erect
            12. piloerection
            13. muscle
            14. relax
            15. shiver
            16. metabolism
            17. decrease
            18. increase