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Organisation of databases and its major grouping
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Nucleotide Sequence Databases
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CEGA
- non-coding sequences
- highly conserved within various group of vertebrates
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JuncDB
- exon-exon junction sequences
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dbSUPER, SEA
- collect sequences of super enhancers
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DFam
- human DNA repeat families
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NPIDB
- nuclear-nuclear interaction
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ARESite
- Subtopic 7
- Subtopic 8
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RNA sequence databases
- Subtopic 1
- Protein sequence databases
- Structure Databases
- Genomics Databases (non-vertebrate)
- Metabolic and Signaling Pathways
- Human and other Vertebrate Genomes
- Human Genes and Diseases
- Microarray Data and other Gene Expression Databases
- Proteomics Resources
- Other Molecular Biology Databases
- Organelle databases
- Plant databases
- Immunological databases
- Cell biology
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Online Updated Molecular Biology Database Collection 2016
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Nucleotide Sequence Databases
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CEGA
- non-coding sequences, highly conserved within various group
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JuncDB
- exon-exon junction sequences
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dbSUPER, SEA
- collect sequences of super enhancers
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DFam
- human DNA repeat families
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NPIDB
- nuclear-nuclear interaction
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ARESite
- AU-rich elements in vertebrate
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JASPAR, HOCOMOCO, ORegAnno and Regular DB
- transcriptional regulation
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BIGNAsim
- DNA dynamics based on molecular dynamics simulations
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Protein sequence databases
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Pfam
- sequence data
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UET
- predicted protein functional sites
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PDBe
- protein structure
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PDBFlex
- statistics of animation between pairs of homologous structure in PDB
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Gene3D
- function predictions to proteomes
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Fun Tree
- evolution of protein function in superfamilies
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Metabolic and Signaling Pathways
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KEGG, MetaCyc, Reactome, WikiPathways, ECMDB, BiGG Models and MNXref/MetaNetX
- metabolomics data, including metabolite standards, protocols, tutorials and analysis tools.
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Viruses, Bacteria, Protozoa and Fungi
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MG-RAST, EBI Metagenomics, probeBASE, and Human Pan-Microbe Communities
- metagenomics resources
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BacWGST
- identify the bacterial strains in samples isolated from infection
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Ensembl Genomes and Bacterial Diversity (BacDive)
- organizal genome diversity
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Genomes of Human and Model Organisms
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DMDD
- collects phenotypic data of mouse mutant embryos
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dbMAE
- provides manually curated data on allele-specific expression of autosomal genes
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Human Diseases and Drugs
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DIDA
- collects data of diseases
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ClinVar, GWASdb, HaploReg
- human genetic variation
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Plants
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IC4R
- all aspect of rice research
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mitochondrial and chemical compounds
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MitoCarta and MitoMiner
- mitochondrial proteins
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MitoAge
- mitochondrial DNA properties from various organisms
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Numbers available
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1685 database
- 15 categories
- 41 subcategories
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Criteria for selection into NAR databases
- Nucleic acid therapeutics
- Intercellular communication via RNA-containing vesicles
- Functional roles of RNA modification
- Single cell gene regulation studies
- Nuclear architecture and functional consequences
- Gene targeting and genome engineering
- Molecular machines and complex molecular assemblages
- Single molecule studies of macromolecular function
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References
- http://www.oxfordjournals.org/our_journals/nar/for_authors/criteria_scope.html
- http://www.oxfordjournals.org/nar/database/c/
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Why we need to group these databases ?
- provide annotation for references
- narrow down search within BLD
- systematic to ease searching
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Why databases are lose and dropped ?
- database are outdated
- no responsive
- content errors
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Why databases are created and shared ?
- as a research tool
- to advance the utility of the Bioinformatics Links Directory
- to test effectiveness and improve any weaknesses
- make the collection better and more meaningful
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Group Name
- SITI KHAIRUNNISA BINTI SALEH
- NUR SHAHIRAH AQILAH BT MOHD SHAFIE
- NURUL ATHIRAH BT ARIFIN
- NURUL NAJWA BT MOHD NASIR
- LADITAH DUISAN