1. defines
   1. drugs
   2. medicine (therapeutic drugs)
2. drugs class
   1. prescription drug
   2. nonprescription drugs
      1. Over-the-counter
   3. controlled drug
      1. Schedule 1-5 drugs
3. bad ideas
   1. Drug abuse
   2. Drug dependence
   3. Drug misuse
   4. A recreational drug
4. Pharmacology
   1. What?
   2. Drugs names
5. Five branches of pharmacology
   1. Pharmaceutics
   2. Pharmacokinetics
      1. Absorption
         1. the rate
            1. Bioequivalent
            2. Bioavailability
         2. 7 Factors That Affect
            1. route
            2. Enteral
            3. First-Pass Effect
            4. How
            5. Where
            6. bypass
            7. Parenteral
            8. Topical
            9. TDDS
            10. Local effect
            11. food
            12. formulation
            13. surface
            14. blood flow
            15. pH
            16. GI motility
      2. Distribution
         1. Protein-binding
         2. Water soluble vs. fat soluble
         3. Blood-brain barrier
         4. Areas of rapid distribution
         5. Areas of slow distribution
      3. Metabolism
         1. what?
         2. primary site liver
            1. how its work?
            2. unwork → toxicity
         3. Delayed drug metabolism results in
            1. Accumulation of drugs
            2. Prolonged action of the effects of the drugs
         4. Stimulating drug metabolism causes:
            1. Diminished pharmacologic effects
      4. Excretion
         1. Kidneys
         2. Liver
         3. Bowel
            1. Biliary excretion
            2. Enterohepatic circulation
      5. Half-life
   3. Pharmacodynamics
      1. 3 phrase
         1. Onset
         2. Peak
         3. Duration
      2. Drug action
         1. Receptor interaction
            1. Agonist
            2. Partial agonist
            3. Antagonist
            4. Competitive antagonist
            5. Noncompetitive antagonist
         2. Enzyme interaction
         3. Nonspecific interactions
      3. Drug effect
   4. Pharmacotherapeutics
      1. Types
         1. Acute therapy (Adrenaline) Maintenance therapy (Tube feeding) Supplemental therapy (Iron supp tablets in anemia) Palliative therapy (Pain relieve) Supportive therapy (Physical exercises) Prophylactic therapy (Preventive)
      2. Monitoring
         1. Therapeutic index
         2. Drug concentration
         3. Patient’s condition
         4. Tolerance and dependence
            1. what
         5. Interactions
            1. alter the action of drug by
            2. Other prescribed drugs
            3. Over-the-counter medications
            4. Herbal therapies
            5. 4 effects
            6. Additive effect
            7. Synergistic effect
            8. Antagonistic effect
            9. Incompatibility
         6. Side effects/adverse drug effects
            1. Adverse drug events
            2. Adverse drug reactions
            3. Side effects
            4. undesire response
            5. types
            6. Idiosyncratic
            7. Hypersensitivity reactions
            8. Drug interactions
            9. adverse effect
            10. Iatrogenic Responses
            11. treatment-induced: Dermatologic Renal damage Blood dyscrasias Hepatic toxicity
            12. Other Drug-Related Effects
            13. Teratogenic
            14. Mutagenic
            15. Carcinogenic
   5. Pharmacognosy