1. Names
   1. pertechnetate - thyroid
   2. methylene diphosphate - bone and blood pool
   3. diethylene triamine pentaacetic acid (DTPA) - renograms
   4. macroaggregated albumin (MAA) - lung perfusion studies
   5. hexamethylpropyleneamine oxime (HMPAO) - brain
   6. non technetium compounds
      1. Thallous chloride - cardiac perfusion
      2. I131 - thyroid therapy
      3. Gallium 67 - malignant disease
2. Image Quality
   1. Quality of radiopharmaceutical
   2. distance patient is to camera
   3. size of patient
   4. patient movement
   5. gamma ray energy
3. bone scans
   1. METS
   2. bone pain
   3. pagets
   4. osteomyelitus
4. Exam
   1. Eat and drink as normal
   2. drink 2-4 cups of water after injection
   3. empty bladder
   4. Tc99m Methylene diphosphonate (MDP) 600-800bq IV
5. Radiopharmaceutical
   1. radioactive compound used for diagnosis and therapeutic treatment of human disease
      1. radionuclide
         1. Topic
            1. nuclide that is radioactive
   2. Functions
      1. Capillary blockage MAA in lung imaging
      2. Diffusion filtration in DTPA/MAG 3 in renal imaging
      3. physiological absorption used in bone imaging
      4. sequestration in infection imaging
      5. active transport in thallium in cardiac imaging
6. TECHNETIUM 99M
   1. Gamma rays
   2. Labelled to a wide range of compounds
   3. generator produced
   4. cheap
   5. Half life 6 hours
7. Equipment
   1. Collimator- parallel hole common. accepts photons only traveling perpendicular
   2. Scintillation crystals - (sodium iodide doped with thallium) Converts gamma rays into light photons
   3. Resolution
      1. Photomultiplier tubes - detect the light photons and generates a signal proportional to amount of light detected
   4. Inherit - ability of the crystal
   5. spatial - distance patient is to camera
8. Safety
   1. Wear aprons/gloves
   2. 5ml syringe
   3. lead shield for syringe
   4. draw from lead pot
   5. draw up from behind lead shield
   6. INPATIENTS- contamined faeces and urine, give letter to ward
   7. OUTPATIENTS- young children
9. Imaging Techniques
   1. Dynamic aquisition - series of frames over the course of which the radioactive tracer distribution alters
   2. Static- radioactivity does not change during acquisition
   3. Gated- dynamic static study whose timings is determined by physiological signals e.g. ECG